NIPT – Non Invasive Prenatal Test

Atila Non-Invasive Prenatal Test Kits

Description

Noninvasive prenatal testing (NIPT) is a method to assess the risk that the fetus will be born with certain genetic abnormalities. Most common NIPT is for aneuploidy of a chromosome which is caused by the presence of an extra or missing copy of a chromosome. The test primarily looks for Down syndrome (trisomy 21), Edwards Syndrome (trisomy 18), and Patau Syndrome (trisomy 13).

Atila also provides test kits for Gender Determination and Fetal Fraction, Fetal Fraction, and test for Genomic DNA Contamination in purified cfDNA.

Details

The Atila Non-Invasive Prenatal Test (NIPT) Kit screens for aneuploidy of chromosomes 21, 18, and 13 in singleton pregnancies. The kit combines Atila’s extreme multiplex PCR technology and ddPCR to accurately quantify the copy numbers of chromosome 21, 18, and 13 in maternal blood cell-free DNA (cfDNA).
Key Features:
  • Highly multiplexed PCR: Enables simultaneous quantification of 3 chromosomes
  • Simple procedures: Direct ddPCR amplification on purified cfDNA
  • Simple data analysis: No complicated bioinformatics required

Fetal fraction assay (FFA) can simultaneously quantify cfDNA and measure fetal fraction in the maternal blood cfDNA. The quantification derived from this assay can be then used for NIPT assay.

Key Features:
  • Highly multiplexed PCR: Enables simultaneous quantification of fetal targets and a reference chromosome.
  • Simple procedures: Direct ddPCR amplification on purified cfDNA
  • Simple data analysis: Simple readout. No complicated bioinformatics required

Technical Specs:

  • Sample Types: purified maternal cfDNA
  • Assay Time: 3 hours
  • Hands-On Time: 60 minutes
  • System Compatibility: C1000 Touch Thermal Cycler, QX200 Droplet Reader
  • Method: Multiplex ddPCRTM

*Order Information:

Cat. No.   

Description                                                                                         

 Size

NIPT-100NIPT kit for T21, T18, and T13100 reactions
NIPT-FF-100NIPT Fetal Fraction Assay100 reactions
NIPT-Y-100NIPT Gender Determination and Fetal Fraction Assay100 reactions
NIPT-GS-100NIPT genomic DNA contamination test100 reactions

*  This product is for research use only in US