BIOREADER® 7000 -F-z-i

Microbiology & Virology > Elispot & Fluorospot Reader
BIOREADER®-7000--F-z-i
Brochure

The BIOREADER® 7000 -F-z-i is particularly suitable for the analysis of live cells in suspension and adherent cells.

This Bioreader® 7000 -F z i provides an automatic zoom range for full field of view 35 – 100 mm Petridish and 6 – 384 well plates.
Providing a resolution of: 30 – 2000 µm for FOCI, 100 – 5000 µm for Plaques or 50 – 2000 µm cell clones.

Model variants:

                 Fluoro filtersets installed         Max. VIS light possible

Alpha                            1                                                3

Beta                              2                                                3

Gamma                        3                                                3

Delta                             6                                                3

All Bioreader® 7000 -F-z-i model variants can be upgraded to max. 8 Fluoro filtersets.

Independence

Bioreader® and EazyReader® operate with all commonly used Elispot/Fluorospot/Plaque/Fluoro-Plaque/CFU assays.
You can choose among all major assay manufactures.

Tests of antiviral substances

This Bioreader® and EazyReader® support testing and development of antiviral substances.

Example#1: The automatic analyses of Plaque reductions assay.

This assay applies diluted doses of a -possibly- antiviral drug into multiwell plates. The Bioreader automatically observes its capability to suppress the formation of plaques (-holes-) in the bacterial lawn.

The ‘Plaque reductions neutralization test’ (PRNT) is a variation of this test. It is an attempt to find an antibody that neutralizes a specific virus. This is a very valuable tool in antiviral vaccine research.

Examplel#2: The automatic evaluation of the Yield reduction assay

In several steps of operation cells are infected in presence of variable doses of a possibly antiviral drug substance.

Thereafter the virus titer is determined in the liquid by use of the plaque or TCID50 assay with of the Bioreader®.

The titer is calculated as the quotient of the positive cells/all cells, taking in account the virus dilution factor and the volume of the inoculum.

Features

  • Automatic of all mechanical functions incl. focus, zoom, aperture.
  • 8 times filter changer.
  • Upgrade option from model alpha to gamma and delta.
  • Dual telecentric illumination for better cytokine quantification.
  • Automatic zoom lens for 6-48 well plates and/or Petri dishes.
  • Fixed focus lens for 96-384 well plates or Petri dishes.
  • Fluoro/UV LED excitation plus 3 types of white light LED illuminations.
  • Hardware is automatically controlled by software measure setup (GxP-locked).
  • No mercury or deuterium lamps required, thus 50T hourly lifetime.
  • Improved suppression of auto-fluorescence, cluster separation, well recognition and cytokine volume quantification.
  • Brand-new generation 7 makes it significant faster and more precise regarding positioning.
  • Single click export to PDF, Microsoft Office® applications.
  • Front loader, automatic door.
  • Dual tele-centric illumination.
  • Loud speaker and interactive training program.
  • Excel/Word/Power Point and LIMS export capabilities.
  • Suitable for research purpose.
  • High contrast/low noise cameras 5-41 MPixel available.
  • Optional automation with plate ‘feeding system’.
  • DQ/IQ/OQ/PQ documention possible.
  • 12 months warranty.
  • EC declaration of conformity and EMC certificate.