Single Cell Dispenser
Fast, precise and efficient single cell dispensing is greatly simplified by MMS automation-ready bench-top single cell dispenser，SCP4000.
Our proprietary intelligent microfluidics technology integrates CMOS circuitry with MEMS devices on a single chip to enable the integration of signal processing and miniaturized and high-throughput liquid handling.
This allows gentle isolation of a variety of single cells directly into 96-well or 384-well plates. The built-in deep learning algorithm automatically identifies only good quality single cells for dispensing based on cell morphology, ensuring a higher clonal recovery rate.
Dispensing single cells for cell line development, single cell omics, synthetic biology, and gene-editing cell cloning applications is now fast, simplified, and user-friendly.
Why our single cell dispenser?
- Fast and efficient single cell dispensing – Single cells are gently dispensed into a 96-well plate in 2 minutes or into a 384-well plate in 8 minutes.
- AI-powered good quality cell recognition – AI-powered image recognition discriminates good quality cells from poor quality ones, ensuring a higher clonal recovery rate.
- Assurance of monoclonality – Capture nozzle images for every dispensing run to assure that only single cells were dispensed into the plate.
- No risk of contamination – Eliminate the risk of cross contamination during dispensing with single-use cartridges.
- Easy to use – Plug-and-play cartridge with no need for manual adjustment, maintenance-free operation enabled by completely tubing less design.
- Robust and reliable – A single cartridge containing over 100 parallel working nozzles avoids experiment failure due to clogging issues.
Who is it for?
- Biopharma/Biotech
- Life Science Startups
- CRO/CDMO
- Academic Institutions / Government Facilities
Applications
Biologics
- Cell line development for production of antibodies, vaccines and recombinant proteins
- Antibody discovery: hybridoma cloning and sub-cloning
Cell Therapy
- Clone selection for iPSCs
- Clone selection for gene-edited cell lines
Gene Therapy
- Cell line construction for research use
- Cell line construction for viral vector production
Single Cell-Omics
- Single cell transcriptomics
- Single cell proteomics
- Single cell multi-omics
Detection Reagent Development
- Cell line development for production of detection antibodies for IVD and reagents
Synthetic Biology
- Single yeast screening for research and production
Single Cell Dispenser SCP4000
Fast, precise and efficient single cell dispensing is greatly simplified by MMS automation-ready bench-top single cell dispenser, SCP4000.
Our proprietary intelligent microfluidics technology integrates CMOS circuitry with MEMS devices on a single chip to enable the integration of signal processing and miniaturized and high-throughput liquid handling.
This allows gentle isolation of a variety of single cells directly into 96-well or 384-well plates. The built-in deep learning algorithm automatically identifies only good quality single cells for dispensing based on cell morphology, ensuring a higher clonal recovery rate.
Dispensing single cells for cell line development, single cell omics, synthetic biology, and gene-editing cell cloning applications is now fast, simplified, and user-friendly.
Biodispensing Cartridge
The single cell dispensing cartridge, which is the core component of the platform, is composed of an intelligent microfluidic chip that integrates CMOS and MEMS technologies to achieve integrated, miniaturized and high-throughput signal sensing, signal processing and liquid handling.
- Highly redundant working nozzles with each independently controllable, reduces clogging-caused issues
- Lifetime of each nozzle is 1 billion times of jettings, far exceeding the required level for cell dispensing
- Completely tubeless design, harmless to cells
- Disposable, free of cross-contamination
Product Details
Simplified and intuitive single cell dispensing workflow with SCP4000.
Reliable liquid transfers from 1–1000 µL with our swappable 1-, 8-, and 96-channel pipettes.
AI-powered algorithm enables automatic identification of good quality single cells.
Harmless cell dispensing ensures high clonal recovery rate.
Specifications
- Single cell rate : >98%, based on AI-powered single cell identification.
- Monoclonality assurance : >99.5%
- Imaging capability : Bright field, numerical aperture=0.3
- Single cell dispensing processing times : ~2min/96-well plate: ~8min/384-well plate
- Number of nozzles : 640, separate control
- Nozzle size : 30μm
- Droplet volume : 24pL
- Collection devices : 6/12/24/48/96/384 well-plates, 8-strip tubes, micro slides, customized matrix
Ancillary
- Power supply : 110V/600W
- Power consumption : 500 W (max.)
- Dimensions : W: 24.0 in. (610mm) x D: 20.5 in. (520mm) x H: 28.3 in. (720mm)
- Weight : 242.5lb (110kg)
- Operating temperature : 15°C to 30°C
- Relative humidity : 20% to 80%