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NOVOstar - Microplate Fluorometer with Integrated
Pipetting System
The NOVOstar is an exciting product for cell-based
kinetic assays and research development. Previously,
cell-based assays required the use of expensive HTS
equipment, which lead to limited accessibility for
scientists in the assay development stage. The NOVOstar
offers the right equipment necessary for cell-based
assays as well as any other assay suitable for the
microplate format.
The NOVOstar has a dual microplate carrier that allows
the user to designate a reagent and measurement
microplate. Furthermore, a transfer pipet is
incorporated into the design for plate-to-plate
transfers along with access to three reagent stations
providing you with flexibility in assay design. In
addition, the unit has up to two injectors that offer
the same variable delivery volume and injection speed as
other BMG LABTECH OPTIMA instruments. Incubation,
shaking, user-defined kinetic sampling rates, and bottom
reading are all standard equipment on the NOVOstar.
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Wide Range of Applications
The NOVOstar can be used for all fluorescence-based
applications that can currently be read by our POLARstar
OPTIMA microplate reader. Due to its integrated
programmable pipettor system, the NOVOstar is especially
well-suited to screen large numbers of compounds in
kinetic cell-based assays or to create a dose response
curve by measuring a wide range of analyte
concentrations. Applications that the NOVOstar is
targeted for include:
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Exceptional Technologies
The NOVOstar has numerous features that cannot be
found on other microplate readers including:
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Integrated Programmable Pipettor System:
The system can be used for plate to plate
transfer, aspirating, dispensing, or mixing
fluids within a microplate well. |
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Dual Microplate Carrier:
Accommodates one reagent plate and one
measurement plate, allowing you to rapidly
screen 96 or 384 different analytes in one
test. |
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Additional Reagent Stations and Reagent
Injectors:
The pipettor system has access to 3
additional reagent stations (e.g. standard
agonist/antagonists, ionophore, washing,
etc.) and you can use any of the two
injectors for dispensing these and other
standard reagents. |
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Fast Kinetics:
The NOVOstar is one of the few instruments
that can measure kinetic events with a
resolution of 20 ms, allowing for calcium
uptake assays to be performed with great
precision. Furthermore, the control software
allows the user to define variable sampling
rates throughout the test run so that data
evaluation can be simplified. |
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Multi-wavelength Detection:
NOVOstar uses a xenon flash lamp that allows
you to measure up to eight
excitation/emission pairs in each well. This
allows you to read dual excitation
fluorophores like fura-2 with speed and
convienence. |
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Precise Temperature Control:
The NOVOstar incorporates BMG LABTECH’s
proprietary heating plates situated above
and below the entire plate movement area
proving for uniform incubation up to 45°C. |
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Real-time Data Observation:
Assay progress can be observed with the
real-time graphics feature that shows the
fluorescence data either as a numerical
value, color gradient, or X-Y plot. |
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Software
BMG LABTECH´s Windows™ based software has an easy to use
control package and powerful data evaluation segment. It
is compatible with the new Windows Vista™ operating
system and is fully compliant with FDA regulation 21 CFR
Part 11.
The control software allows flexible definition of
microplate layouts, filter selection, interval and
injection times, as well as measurement frequency,
heating, and shaking parameters. During measurement, it
is possible to observe the data with the Real Time well
display feature, which allows viewing of raw values,
ratios, curves, or even color coded pictorials.
The evaluation software provides all the macros needed
for fast data calculation. Five pre-programmed
worksheets allow averaging of replicates, blank
subtraction, undilutions, signal plots, slopes, max
values, quantitation, averages, %CVs, standard curves,
and calculation of unknowns and much more.
Windows Vista is a trademark of Microsoft Corporation.
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