Human Genetic Diseases Kits

ViennaLab, founded 1990, develops and manufactures products for medical in-vitro diagnostics in the field of genetic diseases and predispositions. The current focus is on cardiovascular diseases and inherited disorders of iron metabolism (haemochromatosis). The range of products also includes Thalassemia, Familial Mediterranean Fever (FMF), Gaucher Disease, Alzheimer and Pharmacogenetics.

All tests include ready-to use reagents for sample prep, amplification and mutation detection. Reliable multiplex amplification protocols provide convenience and allow testing of samples with very limited volumes. Using the straightforward StripAssay format, testing for twenty and more mutations may be completed in less than five hours without costly equipment. Instrumentation is available for automated processing of StripAssays.
 

Thalassemia	α-globin StripAssay	Detection of 21 alpha globin gene mutations/deletions
	ß-globin StripAssays	Detection of 47 ß-globin gene mutations/deletions
Haemochromatosis	Haemochromatosis StripAssay A	Detection of 18 mutations: twelve HFE mutations, four TFR2 mutations and two FPN1 mutation
	Haemochromatosis StripAssay B	Detection of 3 HFE gene mutations: C282Y, H63D, S65C
Cardiovascular Disease	CVD StripAssay	Testing for 12 mutations / polymorphisms associated with cardiovascular disease
	CVD StripAssay A	Testing for 8 genetic variants predisposing to atherosclerosis
	CVD StripAssay T	Testing for 9 genetic variants predisposing to venous thromboembolism
	FV-PTH StripAssay	Detection of the Factor V Leiden and Prothrombin gene mutations
	FV-PTH-MTHFR StripAssay	Detection of the Factor V Leiden, Prothrombin and MTHFR gene mutations
	FV StripAssay	Detection of the factor V gene mutation FV:Q506 (FV Leiden)
	PTH StripAssay	Detection of the prothrombin gene mutation G20210A
	MTHFR StripAssay	Detection of the MTHFR gene mutation C677T
	PGX-Thrombo StripAssay	Testing for CYP2C9 and VKORC1 variants associated with anticoagulant dose requirements (Coumadin, Marcumar, Sintrom)
Familial Mediterranean Fever	FMF StripAssay	Detection of 12 MEFV gene mutations
Lactose / fructose Intolerance	Sugar Intolerance StripAssay	Detection of two lactase(LCT) gene mutations and four aldolase B gene mutations
Alzheimer	ApoE StripAssay	Determination of isoforms apo E2, E3 and E4
Gaucher Disease	Gaucher Disease StripAssay	Detection of 8 glucocerebrosidase (GBA) gene mutations and two recombinant alleles
Pharmacogenomics	PGX-Thrombo StripAssay	Testing for CYP2C9 and VKORC1 variants associated with anticoagulant dose requirements (Coumadin, Marcumar, Sintrom)
	PGX-HIV StripAssay	Testing for genotypes associated with response to HIV highly active anti-retroviral therapy (HAART)
	PGX-5FU StripAssay	Detection of DPD allelic variant IVS14+1 G->A associated with toxicity of 5-FU therapy
	KRAS StripAssay	Ultra-sensitive detection of codon 12/13 mutations.
Oncology	PGX-5FU StripAssay	Detection of DPD allelic variant IVS14+1 G->A associated with toxicity of 5-FU therapy
	KRAS StripAssay	Ultra-sensitive detection of codon 12/13 mutations.

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