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NEPHELOstar - The Unique Laser-Based Microplate
Nephelometer
The NEPHELOstar microplate nephelometer detects
particles in liquid samples by measuring forward
scattered light when a laser beam is directed through
the solution. This scattered light is detected at angles
of up to 80 degrees, making it approximately thirty
times more sensitive than traditional transmission
readers that measure the reduction in direct light
passing through a sample well.
Flexibility and performance of the NEPHELOstar
nephelometer allow more applications to be adaped to
microplate-based laser nephelometry than ever before:
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Automated drug solubility screening |
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Microbial growth kinetics monitoring |
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Precipitation and polymerization monitoring |
The intensity and beam diameter of the laser light can
be adjusted in the easy to use Software, and this allows
measurement of light scatter in colored or turbid
solutions. In addition, the flexible beam diameter
allows measurement in 24, 48, 96 and 384-well microplate
format.
These features, along with BMG LABTECH´s Digital Photon
Integration (DPI) technology and a detection angle of
80°, ensure that the NEPHELOstar nephelometer is
approximately thirty times more sensitive than
conventional transmission readers.
Temperature-regulated heating plates above and below the
entire plate movement area provide uniform incubation up
to 38°C.
Developed to meet high-throughput demands, this
microplate-based nephelometer is faster than
conventional solubility detection methods with the
highest sensitivity and flexibility.
Self-monitoring laser diode
The light source is a red laser with a wavelength range
of 635 nm. A laser diode has the advantage of higher
stability than other light sources which gives better
precision. The laser intensity can be adjusted via the
software.
Variable laser beam width
An exclusive feature of the NEPHELOstar: the ability to
adjust laser beam width. With a narrow beam width,
liquid surface effects (meniscus effects) are minimized.
Reads 384-well plate formats
The NEPHELOstar is the only microplate nephelometer with
the ability to read 384-well plates with excellent
sensitivity. Use less sample and produce more data per
plate.
Full-cone angle detection system
With the most advanced detection system, the NEPHELOstar
nephelometer can integrate the largest scattering angle,
up to 80°
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